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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 24.55
Human Site: Y1326 Identified Species: 45
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 Y1326 E K L L R H H Y E Q Q Q E D L
Chimpanzee Pan troglodytes XP_512012 1846 210165 R1299 D K I E E I E R E I I K Q E E
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 Y1308 E K L L R H H Y E Q Q Q E D L
Dog Lupus familis XP_536627 1977 223828 Y1303 E K L L R H H Y E Q Q Q E D L
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 Y1315 E K L L R H H Y E Q Q Q E D L
Rat Rattus norvegicus Q9JIX5 2581 290674 L1570 D E S Y K K H L K H Q C N K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 C1736 R K H L K H H C N K V L L R V
Frog Xenopus laevis NP_001080504 1893 214670 Y1313 E K L L R H H Y E Q Q Q E D L
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 N1556 E L I T P P E N G R E P Q A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 Y1309 V K L L R H H Y E Q H Q E D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 T1206 T E V I K E G T E E Q D P N Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 V838 A A L E A Q R V A A E S K S S
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 F921 G E E F L K Q F E V T D Y K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 13.3 N.A. N.A. 26.6 100 13.3 N.A. 80 N.A. 13.3 N.A.
P-Site Similarity: 100 46.6 100 100 N.A. 100 46.6 N.A. N.A. 46.6 100 40 N.A. 86.6 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 0 0 0 8 8 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 0 0 0 16 0 47 0 % D
% Glu: 47 24 8 16 8 8 16 0 70 8 16 0 47 8 8 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 54 62 0 0 8 8 0 0 0 0 % H
% Ile: 0 0 16 8 0 8 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 62 0 0 24 16 0 0 8 8 0 8 8 16 0 % K
% Leu: 0 8 54 54 8 0 0 8 0 0 0 8 8 0 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 8 8 0 0 0 0 0 8 8 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 47 54 47 16 0 0 % Q
% Arg: 8 0 0 0 47 0 8 8 0 8 0 0 0 8 0 % R
% Ser: 0 0 8 0 0 0 0 0 0 0 0 8 0 8 8 % S
% Thr: 8 0 0 8 0 0 0 8 0 0 8 0 0 0 0 % T
% Val: 8 0 8 0 0 0 0 8 0 8 8 0 0 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 47 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _